That was Nuno Espirito Santo’s side’s second defeat in a row, following a 4-0 thrashing by Liverpool.
Here’s all you need to know ahead of the top-flight clash:
The game kicks off at 6pm BST at Molineux.
The match will air live on Amazon Prime.
Moutinho will miss out due to his red card against Villa, while Raul Jimenez’s recovery from a fractured skull will keep him out for an unspecified period of time. Jonny, meanwhile, is a long-term absentee for the hosts, and Willy Boly is not expected to return just yet.
Christian Pulisic is back in the Chelsea squad but is unlikely to feature – until the latter stages of the game, at the very least. Meanwhile, fellow wingers Callum Hudson-Odoi and Hakim Ziyech are not due to return until Boxing Day – if not later.
Wolves: Patricio; Semedo, Coady, Saiss, Marcal; Neves, Dendoncker; Traore, Podence, Neto; Silva
Chelsea: Mendy; James, Zouma, Silva, Chilwell; Kante, Jorginho, Mount; Havertz, Giroud, Werner
Wolves did well to battle to a win against Arsenal after Jimenez’s injury, but they have not quite looked themselves in their fixtures since. Chelsea, meanwhile, slipped up last time out but should have the quality to bounce back here. Wolves 1-2 Chelsea.