The title race could be partially shaped by the meeting, with Leicester second-placed as they enter the tie on 27 points – four behind champions and leaders Liverpool – and United in third spot, just one point behind Brendan Rodgers’ hosts.
Both teams grabbed three points at the weekend, with Leicester defeating Jose Mourinho’s Spurs 2-0 at the Tottenham Hotspur Stadium before United thrashed Leeds 6-2 in a wild contest at Old Trafford.
The stage is therefore set for an entertaining fixture between the Foxes and Ole Gunnar Solskjaer’s players.
Here’s everything you need to know about the top-flight meeting.
The game will kick off at 12.30pm at the King Power Stadium on Saturday.
The match will air live on BT Sport 1 HD and BT Sport Ultimate, and subscribers can also stream it live on the BT Sport website and app.
Leicester: Schmeichel; Justin, Fofana, Evans, Castagne; Ndidi, Tielemans, Albrighton, Maddison; Barnes, Vardy
Manchester United: De Gea, Lindelof, Bailly, Maguire, Shaw, Fred, McTominay, James, Fernandes, Rashford, Martial.
This one could be full of goals, just like Man United’s win over Leeds at the weekend. As such, it feels like a somewhat unpredictable fixture, but an entertaining draw might just be on the cards. Leicester 2-2 Man United.
This weekend get a £10 free bet with Betfair, when you bet £10 on a Same Game Multi on the Premier League. Terms: Min £10 Same Game Multi bet on any EPL match this Fri – Sun. Free bet valid for 72 hours, awarded at bet settlement. Excludes cashed out bets. T&Cs apply.